Ravier – L Capsules
Rabeprazole 20 mg + Levosulpiridemg 75 mg SR Capsules
Irritable bowel syndrome with constipation (IBS-C) & Gastroparesis.
Rabeprazole sodium : is a proton pump inhibitor. It is a prodrug after administration it diffuses in to the parietal cell of the stomach and accumulates in the secretory canaliculi. Inhibits the exchange of extracellular K+ for intracellular H+ ion and thereby decreases gastric acid secretion.
Levosulpiride : is a sulpiride isomer that exerts its prokinetic action through a dual mechanism: 1) as a D(2) dopamine receptor antagonist and 2) as a serotonin 5HT(4) receptor agonist, conferring this drug with a cholinergic effect. Levosulpiride is effective in delayed gastric emptying and may be related to its action on the gastric motor function.
Diarrhoea, Nausea, Headache.
Hepatic impairment, Monitor gastric malignancy.
One capsule once daily.
Storage conditions :
Store at 15 – 30 degree C in a tightly closed container. Protect from light.